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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Medchemcomm. 2014 May 16;5(8):1092–1105. doi: 10.1039/C4MD00081A

Figure 2.

Figure 2

A comparison of the (A) normal translation process leading to functional protein production, (B) translation which is interrupted by a premature termination codon (PTC) leading to a truncated non-functional protein production, and (C) translation process which was restored by a read-through inducing compound such as an aminoglycoside. Terminal codons and PTCs are highlighted in yellow, aminoglycoside in green.