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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Pain. 2014 Jun 2;15(8):878–885. doi: 10.1016/j.jpain.2014.05.006

Figure 3.

Figure 3

Total norepinephrine (NE) content in the ventral striatum are significantly increased in the cuff group and highly correlated with mechanical thresholds. A) NE content normalized to total protein in the ventral striatum was measured with HPLC. Two weeks after nerve injury, the cuff group had significantly elevated NE, compared to the naïve group. The sham group was not significantly different, although the variability was greater in this group. Data represented as box plot with horizontal line representing the mean, the outer box limits representing the interquartile span, and the whiskers the furthest data point. Groups were compared with a Kruskal-Wallis ANOVA followed by Dunns’ multiple comparison post hoc analysis. *=p<0.05, n=7–8. B) NE content normalized to total protein in the ventral striatum were not correlated with mechanical thresholds in sham animals, but were highly correlated in cuff animals two weeks after nerve injury. Correlation was performed with Pearson’s correlation. n=7.