Extended Data Figure 3. Topologies and three-dimensional structures of tRNA and the TYMV TLS.
a, Top: The topology of a canonical tRNA is shown in rainbow color with the 5′ end in blue and the 3′ end in red. The attached amino acid is shown (aa or val) and structural features are labeled: T= T-loop, D= D-loop, AC= anticodon loop, V= variable loop. The 5′ and 3′ ends of the RNA are shown. Bottom: Ribbon representation of the backbone of tRNAPhe roughly colored to match the cartoon diagram. b, Same as panel a, but for the TYMV TLS. The location of the UPD (grey dashed box) and gRNA (grey dashed line connected to the 5′ end) are shown on the top diagram.