Fig. 3.

“Walking” in the domain network. A putative evolutionary path, to demonstrate the relationships between connected domains. The path, taken from the major connected component, passes through eight domains from five different SCOP folds of the alpha/beta class. The aligned motifs are marked in orange or cyan; residues shared by the motifs in both directions along the path are in magenta. The number of residues, rmsd, and percent sequence similarity (using BLOSUM62) of the aligned motifs are indicated.