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. 2014 Jul 16;57(15):6729–6738. doi: 10.1021/jm5007885

Table 2. Corrector Activities of Aniline-Varied Constrained Bithiazoles 9a/10a and 9g–j/10g–j Relative to Bithiazole corr4a.

corr4a:^a V_max = 475 μM/s, IC₅₀ = 6.0 μM
	9a,g–j n = 1			10a,g–j n = 2
compound	V_max (μM/s)	IC₅₀ (μM)	compound	V_max (μM/s)	IC₅₀ (μM)
9a	336	2.3	10a	512	4.1
9g	366	6.9	10g	198	2.1
9h	509	7.2	10h	280	5.2
9i	336	2.2	10i	291	5.2
9j	485	3.6	10j	243	0.9

^a

Corrector activity of benchmark bithiazole corr4a.