Table 1. Comparison of Statistics for Strongly and Weakly Interacting Interfacial β-Strands.
| strongly interacting β-strands (14 940) | weakly interacting β-strands (38 027) | all interfacial β-strands in PPIs (52 967) | |
|---|---|---|---|
| interface strand length, residues | 5.9 ± 2.3 | 4.4 ± 1.6 | 4.8 ± 2.0 |
| no. of hot spot residues | 2.5 ± 0.87 | 0.53 ± 0.49 | 1.1 ± 1.1 |
| per-residue ΔΔG, REU | 1.2 ± 0.65 | 0.47 ± 0.40 | 0.67 ± 0.57 |
| per-residue ΔSASA, Ǻ2 | –41 ± 20 | –22 ± 16 | –27 ± 19 |
| hot spot residue ΔΔG, REU | 2.4 ± 1.6 | 2.0 ± 0.96 | 2.1 ± 1.1 |
| % contribution to ΔΔGcomplex | 22 ± 15 | 9.7 ± 12 | 13 ± 14 |
| % contribution to ΔSASAcomplex | 17 ± 13 | 9.4 ± 11 | 11 ± 12 |
| distance between first and last hot spot residue, Å | 3.9 ± 1.8 | n/a | n/a |