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. Author manuscript; available in PMC: 2014 Aug 18.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Mar 23;33(6):1089–1096. doi: 10.1111/j.1530-0277.2009.00930.x

Fig. 2.

Fig. 2

GABA currents as a function of the ratio of α2, β2 and γ3 subunit mRNAs. A. Peak current amplitudes in response to 10 μM GABA in oocytes injected with either 2:2:1 or 6:2:1 or 0.5:2:1 ratios of α2:β2:γ3 subunit mRNAs. B–C. GABA concentration-response curves in oocytes injected with either 2:2:1 (B) or 6:2:1 (C). Peak currents at each GABA concentration were normalized to the current at 30 μM GABA for each oocyte and averaged within groups. Data are presented as mean ± SE. The solid line through the data indicates the non-linear regression fit with the correlation coefficient (R2) and calculated EC50 values below. Dotted lines indicate the location of EC50 and EC20 on each graph.