. 2014 Jul 16;57(15):6718–6728. doi: 10.1021/jm500786c

Table 1. Cytotoxicity^a for Porphyrin Conjugates Using Human Glioma T98G Cells and Major Localization Sites in Human HEp2 Cells.

compd	dark toxicity IC₅₀ (μM)	phototoxicity IC₅₀ (μM)	major sites of localization
1	>400	>100	Lyso, Mito, Golgi
3	>400	>100	Mito, Golgi, ER
4	>400	>100	Lyso, Mito, Golgi
5	>400	>100	Lyso, Mito, Golgi
6(17)	296	>100	Lyso, Mito, ER
7	>400	>100	Lyso, Mito, Golgi
8	>400	>100	Lyso, Mito, Golgi

CellTiter Blue assay; light dose ∼ 1.5 J/cm².

Table 1. Cytotoxicitya for Porphyrin Conjugates Using Human Glioma T98G Cells and Major Localization Sites in Human HEp2 Cells.