. 2014 Jun 11;9(8):1869–1876. doi: 10.1021/cb5001263

Table 1. EC50 of Prolonged Treatment of LU102 and PR709A in P. falciparum and HFF^a.

	treatment time (h)	P. falciparum EC50 (μM)	HFF EC50 (μM)	selectivity (HFF/Pf)
LU102	24	0.252 ± 0.006	11.47 ± 0.033	46
LU102	72	0.170 ± 0.004	5.12 ± 0.12	30
PR709A	24	0.50 ± 0.02	245 ± 13	490
PR709A	72	0.29 ± 0.01	165 ± 3	569

24 and 72 h treatment of ring stage parasites are shown. For 24 h treatment, cells are treated, washed, and placed in new media for a further 48 h of growth. EC50s are expressed as mean ± standard deviation. Selectivity is determined as the ratio of EC50 in HFF over EC50 in P. falciparum.

Table 1. EC50 of Prolonged Treatment of LU102 and PR709A in P. falciparum and HFFa.

Table 1. EC50 of Prolonged Treatment of LU102 and PR709A in P. falciparum and HFF^a.