Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
MOA studies of compound 1. (A) Compound 1 is competitive with the peptide substrate, as its IC50 values increased linearly with H4 peptide concentrations. (B) Compound 1 is noncompetitive with the cofactor SAM, as its IC50 values remained constant in the presence of increasing concentrations of SAM.
