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. 2014 Jul 25;57(15):6468–6478. doi: 10.1021/jm5008352

Table 1. Effects of Compound NIT on the Michaelis–Menten Kinetics of WT and MDR HIV-1p.

    compound NIT (μM)
    0 100 150
WT Vmax (nM/s) 44 ± 3 35 ± 3 34 ± 3
  Km (μM) 91 ± 8 144 ± 18 184 ± 26
   
MDR Vmax (nM/s) 42 ± 6 30 ± 2 30 ± 4
  Km (μM) 171 ± 36 246 ± 21 359 ± 66