Table 1.
Cytotoxicity and clastogenicity of lead chromatea
Treatment (μg/cm2 LC) | Relative survival (% of control) | Percent of metaphases with damageb,c | Total damage in 100 metaphasesb,c | Percent of apoptosis |
---|---|---|---|---|
0d | 100 | 2 ±0.4 | 2 ±0.4 | 2.9 ±0.5 |
0.1 | 83 | 9 ±1.1e | 9 ±1.2e | 3.3 ±0.2 |
0.5 | 66 | 23 ±2.9e | 27 ±4.2e | 4.1 ±0.7 |
1.0 | 56 | 34 ±1.9e | 42 ±3.0e | 4.2 ±0.2 |
5.0 | 8 | NMf | NM | 6.8 ±0.7 |
Average of three experiments.
±Standard error of the mean.
Average of five experiments.
0: vehicle control (acetone).
Significantly (p < 0.001) different compared to vehicle control.
NM: no metaphases.