Table 1.
Human orthologues demonstrating proximity to GWAS peaks
| Gene | Source | RNASeq-Retina | RNASeq-RPE/Choroid/Sclera | Chr., SNP ID | Human Diseases |
|---|---|---|---|---|---|
| BMP2K | Yeast | + | + | 4,rs9307551 | NA |
| EXOC6 | Yeast | + | + | 10,rs10882165 | NA |
| GIGYF2 | Yeast | + | + | 2,rs1656404, rs1881492 | Parkinson Disease |
| IDE | Yeast | + | + | 10,rs10882165 | Alzheimer Disease |
| PAN2 | Yeast | + | + | 12,rs3138144 | NA |
| PIP5K1B | Yeast | + | + | 9,rs11145465 | Friedreich ataxia |
| PM20D1 | Yeast | + | + | 1,rs1652333 | Parkinson Disease |
| PRKACG | Yeast | − | − | 9,rs11145465 | NA |
| PRKG2 | Yeast | + | + | 4,rs1960445 | Dwarfism |
| RPS26 | Yeast | + | + | 12,rs3138144 | Diamond-Blackfan Anemia |
| SCO1 | Yeast | + | + | 17,rs2969180 | Cytochrome C Oxidase Deficiency |
| SLC38A6 | Yeast | + | + | 14,rs1254319 | NA |
| SMARCC2 | Yeast | + | + | 12,rs3138144 | NA |
| TMEM30B | Yeast | + | + | 14,rs1254319 | NA |
| TOX | Yeast | + | + | 8,rs7837791 | NA |
| ZADH2 | Yeast | + | + | 18,rs12971120 | NA |
| DIS3L2 | Yeast | + | + | 2,rs1656404 | Perlman Syndrome |
| IREB2 | Yeast | + | + | 15,rs4778879 | COPD |
| ZADH2 | Yeast | + | + | 18,rs12971120 | NA |
| DIS3L2 | Yeast | + | + | 2,rs1881492 | Perlman Syndrome |
| CNOT2 | Monkey | + | + | 12,rs12229663 | Dengue Virus |
| IDH3a | Monkey | + | + | 15,rs4778879 | NA |
| TMEM200A | Chicken | + | + | 6,rs12205363 | NA |
| FM189A2 | Chicken | + | + | 9,rs11145465 | NA |