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. 2014 Aug 18;9(8):e104477. doi: 10.1371/journal.pone.0104477

Table 2. Distribution of the characteristics of the study population by groups, intervention (tranexamic acid plus phenylephrine) versus control (phenylephrine alone).

Intervention (n = 30) Control (n = 30)
Characteristics Number Percent Number Percent P value
Gender 0.292
Male 16 53.3 20 66.7
Female 14 46.7 10 33.3
Previous functional endoscopic sinus surgery 0.278
Yes 6 20.0 3 10.0
No 24 80.0 27 90.0
Polyposis 0.580
None 9 30.0 12 40.0
Grade I 9 30.0 11 36.7
Grade II 10 33.3 6 20.0
Grade III 2 6.7 1 3.3
Characteristics Mean SD Mean SD P value
Age (yr) 37.43 11.75 34.10 9.61 0.234
Duration of surgery (min) 114.00 37.93 102.73 25.36 0.182
Systolic blood pressure (mmHg) 100.27 7.48 102.83 7.90 0.201
Diastolic blood pressure (mmHg) 62.93 9.76 67.60 9.22 0.062
Heart rate (/min) 79.33 8.53 76.23 8.95 0.175
Mean arterial pressure (mmHg) 75.27 8.17 79.27 8.71 0.072
Total score (CT scan) 16.90 5.74 16.93 5.32 0.982
Hemoglobin (mg/dl) 14.33 1.65 14.36 1.52 0.955
Hematocrit (%) 44.13 0.70 43.69 4.17 0.667
Bleeding time (min) 2.00 0.49 1.84 0.55 0.242
Prothrombin time (s) 12.37 0.49 12.43 0.57 0.628
Partial thromboplastin time (s) 32.60 2.74 33.53 2.67 0.187
International normalization ratio 1.04 0.05 1.04 0.05 1.000
Platelet count (/mcl) 287166.70 95965.54 275633.30 67941.90 0.593