Skip to main content
. 2014 Aug 18;9(8):e105062. doi: 10.1371/journal.pone.0105062

Table 1. Top Associations between SNVs and BMI-Related Traits.

Phenotype n analyzed Chr SNV position context nearest gene (s) RA AA RAF β se p-value
BMI 5,343 5 rs955423 165652228 intergenic TENM2 A C 0.610 0.335 0.066 3.45·10−7
BMI 5,343 4 rs3096490 110198580 intronic COL25A1 G A 0.529 0.317 0.063 5.32·10−7
BMI 5,343 5 rs1392280 165608261 intergenic TENM2 G A 0.659 0.332 0.067 6.90·10−7
BMI 5,343 15 rs1426654 46213776 exonic SLC24A5 A G 0.510 0.325 0.066 7.54·10−7
BMI 5,343 4 rs794149 110179691 intronic COL25A1 A G 0.521 0.314 0.064 8.36·10−7
BMI 5,343 4 rs3096483 110189985 intronic COL25A1 T C 0.524 0.313 0.063 8.37·10−7
Change in BMI 4,983 5 rs10041997 120226210 intergenic PRR16,FTMT A G 0.518 0.138 0.027 4.40·10−7
Change in BMI 4,983 5 rs1347155 171901953 intergenic SH3PXD2B,NEURL1B T C 0.042 0.341 0.068 4.97·10−7
Change in BMI 4,983 2 rs7565158 213302215 intergenic ERBB4,MIR4776-2 A C 0.495 0.136 0.027 6.34·10−7
Height 5,344 15 rs8042988 87213283 intronic ACAN A G 0.621 0.006 0.001 3.81·10−7
Height 5,344 14 rs4898878 55462859 intergenic LINC00520,PELI2 A G 0.709 0.006 0.001 9.07·10−7
Underweight 4,474 14 rs12882679 78916991 intronic NRXN3 G A 0.687 0.057 0.012 9.57·10−7
Overweight 3,244 14 rs1475010 25206451 intergenic STXBP6,NOVA1 C A 0.307 0.060 0.012 5.74·10−7
Overweight 3,244 14 rs8181969 25214651 intergenic STXBP6,NOVA1 C A 0.305 0.059 0.012 8.49·10−7

AA: Alternative Allele; the allele associated with a decrease in the phenotype; BMI: Body Mass Index; Chr.: Chromosome; Overweight: BMI ≥23 kg/m2; compared to normal weight; Position: From build 36.1; RA: Risk allele; the allele associated with an increase in the phenotype; RAF: Risk Allele Frequency; SNV: Single Nucleotide Variant; se: Standard Error; Underweight: BMI <18.5 kg/m2, compared to normal weight.