Table 3. Univariate analysis demonstrating factors associated with OS and PFS.
Factor | No. | OS p-value | PFS p-value |
Sex | 0.149 | 0.774 | |
Male | 89 | ||
Female | 39 | ||
Age (years) | 0.865 | 0.103 | |
> 72 | 57 | ||
≤ 72 | 71 | ||
Charlson score | 0.947 | 0.314 | |
≥ 1 | 42 | ||
< 1 | 86 | ||
Pathological grade | 0.847 | 0.683 | |
Well differentiated | 10 | ||
Moderately differentiated | 47 | ||
Poorly/undifferentiated | 45 | ||
Unknown | 26 | ||
Location | 0.325 | 0.634 | |
Upper third | 38 | ||
Middle third | 69 | ||
Lower third | 21 | ||
Primary tumor length | 0.039 | 0.169 | |
≤ 5 cm | 78 | ||
> 5 cm | 50 | ||
T stage | 0.000 | 0.007 | |
T1-T2 | 25 | ||
T3-T4 | 103 | ||
N stage | 0.804 | 0.359 | |
N0 | 26 | ||
N1 | 102 | ||
M stage | 0.012 | 0.041 | |
M0 | 78 | ||
M1 | 50 | ||
Radiation dose (Gy) | 0.056 | 0.226 | |
< 60 | 49 | ||
≥ 60 | 79 | ||
Treatment modality | 0.008 | 0.004 | |
CCRT | 73 | ||
RT alone | 55 |
Abbreviations: OS, overall survival; PFS, progression-free survival; CCRT, concurrent chemoradiotherapy; RT, radiotherapy.