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. 2014 Aug 18;9(8):e105270. doi: 10.1371/journal.pone.0105270

Table 3. Univariate analysis demonstrating factors associated with OS and PFS.

Factor No. OS p-value PFS p-value
Sex 0.149 0.774
Male 89
Female 39
Age (years) 0.865 0.103
> 72 57
≤ 72 71
Charlson score 0.947 0.314
≥ 1 42
< 1 86
Pathological grade 0.847 0.683
Well differentiated 10
Moderately differentiated 47
Poorly/undifferentiated 45
Unknown 26
Location 0.325 0.634
Upper third 38
Middle third 69
Lower third 21
Primary tumor length 0.039 0.169
≤ 5 cm 78
> 5 cm 50
T stage 0.000 0.007
T1-T2 25
T3-T4 103
N stage 0.804 0.359
N0 26
N1 102
M stage 0.012 0.041
M0 78
M1 50
Radiation dose (Gy) 0.056 0.226
< 60 49
≥ 60 79
Treatment modality 0.008 0.004
CCRT 73
RT alone 55

Abbreviations: OS, overall survival; PFS, progression-free survival; CCRT, concurrent chemoradiotherapy; RT, radiotherapy.