Table 2. Model fitting for siRNA/BSA release profiles from CA-PEI micelles at pH 5 and 7.4.
siRNA | ||||||||
pH | zero-order | first-order | Korsmeyer-Peppas | Higuchi | ||||
K | R2 | K | R2 | n | R2 | K | R2 | |
5 | 0.1976 | 0.7478 | 0.0017 | 0.6161 | 0.1848 | 0.9553 | 3.318 | 0.9101 |
7.4 | 0.1746 | 0.6913 | 0.0018 | 0.5494 | 0.2111 | 0.9304 | 2.987 | 0.8732 |
BSA | ||||||||
5 | 0.1803 | 0.791 | 0.002 | 0.6539 | 0.2129 | 0.9745 | 2.995 | 0.9398 |
7.4 | 0.1732 | 0.7875 | 0.0024 | 0.5776 | 0.2684 | 0.9136 | 2.8602 | 0.9244 |