Figure 8. Comparison of the viral compositional summary of control and CVD samples by deep shotgun sequencing.
(A) Major compositional differences include (i) relatively higher abundance of families Siphoviridae, Myoviridae, Podoviridae and Inoviridae among CVD samples than healthy individuals (ii) relatively higher abundance of families Mimiviridae, Poxviridae, Phycodnaviridae, Iridoviridae, Anelloviridae and Geminiviridae among healthy control samples (iii) negligible presence of the family Retroviridae in all the samples. (B) Relative occurrence of Bacteriophages and Eukaryotic viruses in the circulating microbiome of CVD patients and healthy controls. An increase in the population of Bacteriophages coupled with a parallel reduction in the population of Eukaryotic viruses in CVD patients is discernible.