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. 2014 Aug 18;9(8):e105393. doi: 10.1371/journal.pone.0105393

Figure 1. Sharing of cis-eQTL associations among different studies.

Figure 1

A. cis-eQTL associations shared between GBM tumors and normal tissues/cell lines in RegulomeDB. Of 985 significant transcript-genotype associations in GBM, 57.1% (24.5%+32.7%) shared the same cis-eQTL/gene pair with cell lines or normal tissues (“Match”); 13.2% (5.3%+7.9%) shared the same cis-eQTLs which are associated with the gene in the neighbor of the target gene identified from GBM (“Match Neighbor”). ReguomeDB variant classification: category 1- known eQTLs for genes; category 6–unknown. B. cis-eQTL associations shared between GBM tumors identified from this study and breast cancer samples identified from a published study. Of 985 significant transcript-genotype associations in GBM, 242 (24.57%) shared the same cis-eQTL associations with breast cancer samples.