Table 2.

CI value of combination of 5-FU and eribulin

Combination ratio	Cell lines
5-FU (μM): eribulin (nM)	MDA-MB-231	MDA-MB-468	MX-1	BT-549
1 : 0.003			0.95	1.12
1 : 0.01	0.61	0.81	0.46	1.27
1 : 0.03	0.58	0.73	0.27	1.08
1 : 0.1	0.60	0.63	0.44	1.08
1 : 0.3	0.63	0.64	0.60	1.18
1 : 1	0.57	0.61	0.73	1.09
1 : 3	0.61	0.70

The CI values were calculated in each combination ratio. The CI values of <1, 1, or >1 indicate synergism, additively, and antagonism, respectively.