Table 2.
Performances of the Xpert®MTB/RIF assay, smear microscopy, and culture using FOB samples for the diagnosis of pulmonary tuberculosis
| |
Performances relative to culture |
Performances relative to final diagnosis |
||
|---|---|---|---|---|
| |
Sensitivity% |
Specificity% |
Sensitivity% |
Specificity% |
| (95% CI) n | (95% CI) n | (95% CI) n | (95% CI) n | |
| Xpert® MTB/RIF assay |
80.0 |
98.6 |
60.0 |
100.0 |
| (57.8-92.5) |
(94.7-99.9) |
(42.3-75.4) |
(96.6-100.0) |
|
| 16/20 |
140/142 |
18/30 |
132/132 |
|
| Smear microscopy |
25.0 |
95.8 |
16.7 |
95.5 |
| (10.8-47.3) |
(90.9-98.3) |
(6.9-34.0) |
(90.2-98.1) |
|
| 5/20 |
136/142 |
5/30 |
126/132 |
|
| Culture |
- |
- |
66.7 |
100.0 |
| (48.7-80.9) |
(96.6-100.0) |
|||
| 20/30 |
132/132 |
|||
|
p-valuea |
0.003 |
0.288 |
0.001
b
|
0.041
b
|
|
0.683
c
|
- |
|||
| 0.0003 d | 0.041 d | |||
ap-values were calculated using the McNemar’s test.
bp-value between Xpert®MTB/RIFassay vs. smear microscopy.
c p-value between Xpert®MTB/RIFassay vs. culture.
d p-value between culture vs. smear microscopy.