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Capsaicin, at lower concentration, mimicked acid-induced effects in esophageal jugular and nodose C fibers. A and B: capsaicin (0.2 μM, 30 min) evoked AP in jugular C fibers and inhibited their response to esophageal distension (n = 6). C and D: capsaicin (0.1 μM, 30 min) did not evoke AP in nodose C fibers but inhibited their responses to esophageal distension (n = 7).
