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Acid-induced effects on esophageal jugular and nodose C fibers
| Acid | AMG9810+Acid | Amiloride+Acid | ||
|---|---|---|---|---|
| Activation response | ||||
| Jugular | Capsaicin (+) | 6/8 | 1/6 | 5/5 |
| Capsaicin (−) | 1/2 | 0/4 | ||
| Nodose | Capsaicin (+) | 1/9 | 2/6 | 0/5 |
| Capsaicin (−) | 0/3 | 0/1 | ||
| Decreased mechanical excitability | ||||
| Jugular | Capsaicin (+) | 8/8 | 0/6 | 3/5 |
| Capsaicin (−) | 1/2 | 4/4 | ||
| Nodose | Capsaicin (+) | 9/9 | 1/6 | 5/5 |
| Capsaicin (−) | 1/3 | 1/1 | ||
Values are number of fibers affected/total number of fibers.
