Table 2.

Clinical characteristics of the COPD patients and healthy controls from ELSA and Whitehall II

	WHII			ELSA
Characteristics	Cases (n = 318)	Controls (n = 1133)	P Value	Cases (n = 364)	Controls (n = 1094)	P Value
Age, yr	45.73 ± 6.1	43.43 ± 5.7	<0.001	71.40 ± 9.6	66.03 ± 8.44	<0.001
Male	199 (63%)	860 (76%)	<0.001	207 (57%)	510 (47%)	<0.001
Ever smoked, %	100	100		100	100
FEV1, liters	2.04 ± 0.68	3.05 ± 0.67	<0.001	1.38 ± 0.60	2.46 ± 0.77	<0.001
FEV1, % predicted	59.16 ± 14.83	84.52 ± 11.79	<0.001	56.16 ± 18.56	99.39 ± 43.43	<0.001
FVC, liters	3.49 ± 0.88	3.96 ± 0.77	<0.001	2.62 ± 0.97	3.20 ± 1.06	<0.001
FEV1/FVC	0.58 ± 0.11	0.77 ± 0.06	<0.001	0.53 ± 0.14	0.78 ± 0.08	<0.001

Data are presented as means ± SD or number with % in parentheses. WHII, Whitehall II.