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. 2014 Aug 18;7(4):648–653. doi: 10.3980/j.issn.2222-3959.2014.04.11

Table 2. Serum Ang-1, Ang-2, VEGF, Tie-2, and Ang-1/Ang-2 ratio levels among the NDR group, NPDR group, and PDR group.

Items NDR (n=50) NPDR (n=58) PDR (n=52) Χ2 P
Ang-1 (ng/mL) 9.31 (7.79-11.64) 10.77 (9.01-12.07)a 9.54 (8.64-11.4) 8.742 0.013
Ang-2 (ng/mL) 2.67 (1.41-4.25) 4.23 (2.51-5.48)b 6.26 (4.16-8.01)b,d 37.033 0.000
Ang-1/Ang-2 2.90 (1.94-6.40) 2.69 (1.81-4.45) 1.49 (1.21-2.20)b,d 27.955 0.000
VEGF (pg/mL) 159.8 (40.8-376.4) 303.2 (80.1-527.1)a 531.2 (299.2-867.6)b,d 28.541 0.000
Tie-2 (ng/mL) 3.54 (2.84-4.45) 3.69 (3.18-4.41) 3.91 (2.65-5.38) 0.910 0.635

aP<0.05 and bP<0.01 vs NDR; dP<0.01 vs NPDR.