Table 2. Serum Ang-1, Ang-2, VEGF, Tie-2, and Ang-1/Ang-2 ratio levels among the NDR group, NPDR group, and PDR group.
Items | NDR (n=50) | NPDR (n=58) | PDR (n=52) | Χ2 | P |
Ang-1 (ng/mL) | 9.31 (7.79-11.64) | 10.77 (9.01-12.07)a | 9.54 (8.64-11.4) | 8.742 | 0.013 |
Ang-2 (ng/mL) | 2.67 (1.41-4.25) | 4.23 (2.51-5.48)b | 6.26 (4.16-8.01)b,d | 37.033 | 0.000 |
Ang-1/Ang-2 | 2.90 (1.94-6.40) | 2.69 (1.81-4.45) | 1.49 (1.21-2.20)b,d | 27.955 | 0.000 |
VEGF (pg/mL) | 159.8 (40.8-376.4) | 303.2 (80.1-527.1)a | 531.2 (299.2-867.6)b,d | 28.541 | 0.000 |
Tie-2 (ng/mL) | 3.54 (2.84-4.45) | 3.69 (3.18-4.41) | 3.91 (2.65-5.38) | 0.910 | 0.635 |
aP<0.05 and bP<0.01 vs NDR; dP<0.01 vs NPDR.