FIG. 7.

In vivo effect of released rhVEGF from dual growth factor releasing scaffolds. rhVEGF release enhanced blood vessel ingrowth (black arrows) 2 weeks after implantation. (a–d) vWF immunostaining of blood vessels within sections of implanted β-TCP scaffolds releasing (a) No rhVEGF; (b) 0.5 μg rhVEGF; (c) 1.0 μg rhVEGF; (d) 10 μg rhVEGF. Positive vWF staining is brown, and circular vWF staining represents a blood vessel. (e) Quantification of the number of blood vessels within the pores of the scaffold. *p<0.009 relative to the no growth factor condition. Scale bars=100 μm. Color images available online at www.liebertpub.com/tea