Table 1.
The National Registers Providing Data for the Study and the Covered Time Period
Danish Civil Registration System (DCRS): 1974–2010 • Identification of the unique personal identification (ID) number as a key identifier of all live-born children in Denmark between January 1, 1990 and December 31, 1999 • Identification of both parents of children in this cohort |
Danish National Hospital Register (DNHR): 1980–2010 • ID number • Lifetime ICD-10 cardiovascular diseases (I00-I99) from all inpatient admissions (since 1980) and outpatient contacts (since 1995) for all children in the cohort and their parents • Holds information on ICD-10 diagnoses, the date of admission, date of discharge, and ID of the hospital |
Danish Psychiatric Central Register (DPCR): 1960–2010 • ID number • Lifetime ICD-10 psychiatric diagnoses from all inpatient admissions (since 1960) and outpatient contacts (since 1995) of all children in the cohort and their parents • Information on date of admission, date of discharge, identification of the hospital, ICD-10 diagnoses, and conditions of admission (voluntary or coercive) for all contacts |
Danish Register of Medical Product Statistics (DRMPS): 1995–2008 • ID number for each prescription • All prescriptions for all children in the cohort and their parents • Information on the anatomical therapeutic chemical (ATC-code), the date of purchase, defined daily doses (DDD), and brand name |
Integrated Database for Longitudinal Labour Market Research (IDA): 1980–2010 • ID number • Age of mother and father • Level and length of education of mother and father • Parental employment status of mother and father on November 1 for each calendar year • Length of unemployment periods for mothers and fathers during each calendar year • Gross income of both parents for each calendar year |
We included the following ATC-codes for stimulants treatment: • Amphetamine (N06BA01) • Dexamphetamine (N06BA02) • Methylphenidate (N06BA04) |
Danish Medical Birth Register (MBR): 1973–2010 • ID number • Apgar score • Birth weight • Birth complications • Maternal smoking during pregnancy |
Cardiovascular risk factors, either in the child or in one of the parents: • Any cardiovascular disease in parents (I00–I99) • Any respiratory disease in parents (J00–J99) • Congenital cardiovascular disease (Q20–28) • Any cardiovascular disease in the child before the age of 5 • Fragile X (Q99.2) • Down syndrome (Q90.x) • Diabetes (E10–14) • Cardiovascular medication (ATC-C code) • Respiratory medication (ATC-R ode) • Neuroleptics (ATC-N05A code) |
ICD 10, International Statistical Classification of Diseases and Related Health Problems, 10th revision.