FIG. 4.

Effect of adenosine on intracellular ATP level of a single C2C12 cell during the 0.1% hypoxic phase. Intracellular ATP of hypoxic cells was expressed as a percentage of that measured in normoxic cells at day 0. With only 19% remained at day 3, ATP of the control group continued to decline until no ATP was detected at day 11. Throughout the hypoxic duration, a higher ATP level was observed in the cells treated with 5 mM adenosine, still maintaining 18% of ATP by day 11 (n=4, Student t-test, *p<0.05). ATP, adenosine triphosphate. Color images available online at www.liebertpub.com/tea