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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cancer Res. 2014 Mar 17;74(11):2962–2973. doi: 10.1158/0008-5472.CAN-13-2421

Fig 4. The expression of Vegfa is reduced by the deletion of tumor stroma cell Wnt7b.

Fig 4

(A) Relative Vegfa mRNA expression in control (C) and mutant (M) MMTV-PyMT tumors at H/A, EC and LC stages. Inset: Immunoblotting for VEGFA and actin control and mutant MMTV-PyMT tumor lysates. (B) Relative sFlt-1 mRNA level in control and mutant MMTV-PyMT tumors at H/A, EC and LC stages. (C, D) Relative expression of Axin2, c-Myc, and CyclinD1 in control and mutant whole tumor (C) and CD31+, CD105+ blood vascular endothelial cells (D). Sample number is shown at the base of each histogram bar. Error bars are SEM.