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. Author manuscript; available in PMC: 2014 Aug 19.
Published in final edited form as: Tuberculosis (Edinb). 2009 Dec;89(0 1):S15–S17. doi: 10.1016/S1472-9792(09)70006-X

Fig. 2.

Fig. 2

Effects of M. tuberculosis aerosol infectious dose from approximately 100 to 105 colony-forming units (CFU) on the number of bacteria that spread to the spleen by day one post-infection in (A) mice and (B) guinea pigs. Aerosol infection with more than 10,000 CFU results in early extrapulmonary spread of tuberculosis to the spleen in both mice and guinea pigs. Data shown are the means and standard deviations of five animals per group.