Table 3.
Characteristics of CRRT in children treated with heparin and citrate.
| Citrate | Heparin | P | |
|---|---|---|---|
| Median (IQR) | Median (IQR) | ||
| Blood flow (mL/min)/weight (kg) | 3.2 (2–3.8) | 5.0 (3.8–5.6) | 0.008 |
| Citrate dose (mmol/L) | 2.6 (2.3–2.9) | — | — |
| Citrate flow (citrate 12 mmol/L) (mL/kg/h) |
67 (50.9–73.7) | — | — |
| Citrate flow (citrate 18 mmol/L) (mL/kg/h) |
28 (21.3–30.8) | — | — |
| Final citrate dose (mmol/L) | 2.9 (2.5–3.2) | — | — |
| Heparin (UI/kg/h) | — | 15 (12–25) | — |
| Extraction rate (mL/h) | 75 (50–97.5) | 60 (50–90) | 0.526 |
| Dialysis (mL/h) | 325 (50–600) | 400 (200–750) | 0.289 |
| Postfilter substitution (mL/h) | 50 (0–50) | 300 (140–500) | 0.026 |
| Total CRRT doses (mL/kg/h) | 69 (52–85) | 59 (44–70) | 0.154 |
| CRRT duration (h) | 155 (92–204) | 166 (92–271) | 0.736 |
IQR: interquartile range.