Table 1.

Symptom Ratings at Baseline and End-Point Over 12 Weeks

	Baseline Mean±SE	End-point Mean±SE	Change Mean (95%CI)	p value
YBOCS
Severity	3.0±0.5	1.8±0.4	−1.2 (−2.4, −0.0)	0.04
Reliability	0.9±0.1	0.9±0.1	0.0 (−0.3, 0.3)	0.9
Obsessions	7.2±1.8	6.2±1.5	−1.0 (−4.9, 2.9)	0.6
Compulsions	9.3±1.6	4.6±1.4	−4.7 (−7.7, −1.7)	0.006
Total	15.9±2.6	10.2±2.0	−5.7 (−10.6, −0.8)	0.03
ABC
Irritability	24.5±2.9	6.8±2.0	−17.7 (−22.0, −13.3)	<0.0001
Lethargy	15.0±2.7	5.1±1.4	−9.9 (−16.2, −3.6)	0.005
Stereotypy	8.1±1.8	1.8±0.8	−6.4 (−10.1, 2.7)	0.003
Hyperactivity	27.9±3.2	6.7±1.9	−21.2 (−26.9, −15.6)	<0.0001
Inappropriate speech	6.4±1.0	2.2±0.6	−4.3 (−5.9, −2.7)	<0.0001
BPRS
Total	69.0±4.7	36.1±4.1	−32.9 (−44.7, −21.1)	<0.0001

YBOCS, Yale–Brown Obsessive Compulsive Scale; ABC, Aberrant Behavior Checklist; BPRS, Brief Psychiatric Rating Scale.