Table 4.
Effect of the test samples on the serum parameters.
| Group | Unit | Statistical mean ± S.E.M. | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Vehicle | NaOx | Hexane extract | EtOAc extract | MeOH extract | LJVO | LCJVO | Cystone | ||
| Creatinine | mg/dL | 1.59 ± 0.04 | 4.06 ± 0.13 | 2.08 ± 0.12 | 2.26 ± 0.16 | 1.98 ± 0.07 | 1.75 ± 0.08 | 1.66 ± 0.10 | 1.46 ± 0.09 |
| Urea nitrogen | mg/dL | 11.17 ± 0.72 | 20.59 ± 1.32 | 18.89 ± 0.97 | 6.89 ± 1.07 | 9.15 ± 0.89 | 6.23 ± 0.70∗ | 5.02 ± 0.39∗∗ | 5.12 ± 0.45∗∗ |
| Uric acid | mg/dL | 1.99 ± 0.65 | 4.08 ± 0.15 | 2.05 ± 0.51 | 1.85 ± 0.05 | 2.19 ± 0.32 | 1.91 ± 0.40 | 1.88 ± 0.23 | 1.80 ± 0.16 |
| Sodium | eEq/L | 3213.42 ± 158.65 | 5144.76 ± 214.63 | 4123.48 ± 186.25 | 4486.32 ± 168.30 | 5026.42 ± 317.49 | 4073.29 ± 250.38 | 4215.82 ± 154.36 | 3961.03 ± 86.40 |
| Potassium | eEq/L | 32.62 ± 1.13 | 64.26 ± 1.08 | 44.31 ± 1.26 | 48.92 ± 1.32 | 50.76 ± 1.25 | 28.30 ± 1.02 | 30.54 ± 0.95 | 24.10 ± 0.80∗ |
| Chloride | mEq/L | 54.24 ± 2.75 | 132.73 ± 5.91 | 155.2 ± 3.67 | 81.96 ± 2.96 | 76.85 ± 3.04 | 74.17 ± 3.16 | 13.20 ± 1.91∗∗∗ | 10.35 ± 1.07∗∗∗ |
| Calcium | mg/dL | 2.74 ± 0.15 | 8.32 ± 0.39 | 7.14 ± 0.76 | 5.92 ± 0.50 | 3.85 ± 0.45 | 4.07 ± 0.36 | 2.53 ± 0.16 | 2.02 ± 0.09∗ |
S.E.M.: standard error of the mean; *P < 0.05; **P < 0.01; ***P < 0.001; test groups were compared to the vehicle.