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. 2014 Aug 4;2014:319534. doi: 10.1155/2014/319534

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Copyright © 2014 Yanfeng Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Comparison of the accuracy of SNPs detected by three strategies. The upper panel is plotted for SNPs across the on-target regions; the lower panel is for the off-target SNPs. From the left to right in each panel are the Ti/Tv ratio ((a) and (b)), Hete/Homo ratio ((c) and (d)), and overlapping rate with SNPs observed in the 1 KG project ((e) and (f)). Uni_M, Uni_L, and Uni_H represent the number of SNPs uniquely identified by the merged, low depth, and high depth strategies, respectively; All_M, All_L, and All_H denote the total number of SNPs identified by the merged, low depth, and high depth strategies, respectively. The x-axis represents each of 92 exome-seq samples.