Table 4.
The in vitro growth of MDA-MB-231 cells as measured by spectrophotometric light absorbance at a wavelength of 540 nm. Values represent mean (SD).
| Cell lines | MDAΔSOCS7 | P | |||
|---|---|---|---|---|---|
| Incubation medium | HGF | ||||
| MDAWT | HGF | 1.8 (0.04) vs. 1.3 (0.1) | <0.001 | ||
| MDApEF6 | 1.8 (0.04) vs. 1.4 (0.02) | <0.001 | |||
|
| |||||
| Pretreatment with U73122 then HGF | |||||
| MDAWT | Pretreatment with U73122 then HGF | 1.3 (0.07) vs. 1.2 (0.08) | 0.49 | ||
| MDApEF6 | 1.3 (0.07) vs. 1.2 (0.14) | 0.73 | |||
|
| |||||
| Cell lines | MDAWT | MDApEF6 | MDAΔSOCS7 | P | |
|
| |||||
| HGF | |||||
| MDAWT | Serum free only | 1.3 (0.1) vs. 0.9 (0.1) | 1.4 (0.02) vs. 0.9 (0.1) | <0.001 (both) | |
| MDApEF6 | 1.3 (0.1) vs. 0.98 (0.05) | 1.4 (0.02) vs. 0.98 (0.05) | <0.001 (both) | ||
| MDAΔSOCS7 | 1.8 (0.04) vs. 1.3 (0.1) | <0.001 | |||