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The in vitro migration of MCF7 as measured by relative wound area (%). Values represent Mean (SD).
| Cell lines | MCF7ΔSOCS7 | P | ||
|---|---|---|---|---|
| Incubation medium | HGF | |||
| MCF7pEF6 | HGF | 31.9 (19.6) vs. 54.7 (15.5) | 0.019 | |
|
| ||||
| Cell lines | MCF7pEF6 | MCF7ΔSOCS7 | P | |
|
| ||||
| HGF | ||||
| MCF7pEF6 | Serum free only | 54.7 (15.5) vs. 73.4 (9.8) | 0.028 | |
| MCF7ΔSOCS7 | 31.9 (19.6) vs. 50.6 (5.9) | 0.045 | ||
|
| ||||
| Pretreatment with U73122 then HGF | ||||
| MCF7pEF6 | HGF | 55.9 (17.2) vs. 54.7 (15.5) | 0.9 | |
| MCF7ΔSOCS7 | 59.8 (20.3) vs. 31.9 (19.6) | 0.005 | ||
