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The in vitro migration of MDA-MB-231 as measured by relative wound area (%). Values represent mean (SD).
| Cell lines | MDAΔSOCS7 | P | ||
|---|---|---|---|---|
| Incubation medium | HGF | |||
| MDApEF6 | HGF | 34.9 (3.8) vs. 58.5 (2) | 0.01 | |
|
| ||||
| Cell lines | MDApEF6 | MDAΔSOCS7 | P | |
|
| ||||
| HGF | ||||
| MDApEF6 | Serum free only | 58.5 (2) vs. 80.2 (4.5) | 0.017 | |
| MDAΔSOCS7 | 34.9 (3.8) vs. 54.3 (8) | 0.017 | ||
|
| ||||
| Pretreatment with U73122 then HGF | ||||
| MDApEF6 | HGF | 71.8 (4) vs. 58.5 (2) | 0.87 | |
| MDAΔSOCS7 | 61.2 (16.2) vs. 34.9 (3.8) | 0.007 | ||
