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The in vitro migration rate of MDA-MB-231 (μm/hr). Values represent Mean (SD).
| Cell lines | MDAΔSOCS7 | P | ||
|---|---|---|---|---|
| Incubation medium | HGF | |||
| MDApEF6 | HGF | 222 (48.1) vs. 104.2 (36.1) | <0.001 | |
|
| ||||
| Cell lines | MDApEF6 | MDAΔSOCS7 | P | |
|
| ||||
| HGF | ||||
| MDApEF6 | Serum free only | 104.2 (36.1) vs. 37.1 (2.6) | 0.008 | |
| MDAΔSOCS7 | 222 (48.1) vs. 138.9 (13.9) | <0.001 | ||
|
| ||||
| Pretreatment with U73122 then HGF | ||||
| MDApEF6 | HGF | 54.2 (10.2) vs. 104.2 (36.1) | 0.046 | |
| MDAΔSOCS7 | 59.3 (58.8) vs. 222 (48.1) | <0.001 | ||
