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. 2014 Jun 17;31(9):2516–2527. doi: 10.1093/molbev/msu192

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© The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 5. — Temporal sampling distinguishes genetic drift from population structure. (A) Constant population size model. (B) Bottleneck model. (C) Replacement model. (D) PC1 stratified by sample time under the constant population size model. (E) PC1 stratified by sample time under the bottleneck model. (F) PC1 stratified by sample time under the replacement model. Each colored circle corresponds to a single-sampled individual except for the large circles at time zero which corresponds to 20 sampled individuals in A, B, and C (in D, E, and F, the 20 individuals sampled at time zero end up on top of each other). F_ST between samples from before and after the bottleneck/replacement events at 5,500 years ago fails to distinguish between the models (F_ST = 0.0154 ± 0.0003 and 0.0153 ± 0.0003, respectively, see fig. 6).