Table 2.
Experimental and calculated BRPP based on HA and SVM.
| No. | Compd. | BRPP/(%) | HA | Residual | SVM | Residual |
|---|---|---|---|---|---|---|
| 1a | Acebutolol | 26.0 | 35.9 | 9.9 | 40.0 | 14.0 |
| 2 | Alprenolol | 85.0 | 61.5 | −23.5 | 72.9 | −12.1 |
| 3 | Amantadine | 67.0 | 58.6 | −8.4 | 61.9 | −5.1 |
| 4 | Amiodarone | 100.0 | 110.9 | 10.9 | 100.3 | 0.3 |
| 5 | Amitriptyline | 94.8 | 100.1 | 5.3 | 90.1 | −4.7 |
| 6a | Aspirin | 49.0 | 56.1 | 7.1 | 45.0 | −4.0 |
| 7 | Betamethasone | 64.0 | 62.9 | −1.1 | 61.0 | −3.0 |
| 8 | Bumetanide | 99.0 | 92.6 | −6.4 | 94.0 | −5.0 |
| 9 | Caffeine | 36.0 | 28.0 | −8.0 | 30.9 | −5.1 |
| 10 | Cefalexin | 14.0 | 41.6 | 27.6 | 41.0 | 27.0 |
| 11a | Chloroquine | 61.0 | 67.7 | 6.7 | 75.6 | 14.6 |
| 12 | Chlorthalidone | 75.0 | 76.8 | 1.8 | 80.0 | 5.0 |
| 13 | Cimetidine | 19.0 | 17.2 | −1.8 | 19.4 | 0.4 |
| 14 | Ciprofloxacin | 40.0 | 40.6 | 0.6 | 43.4 | 3.4 |
| 15 | Diphenhydramine | 78.0 | 83.2 | 5.2 | 83.9 | 5.9 |
| 16a | Furosemide | 98.8 | 85.8 | −13.0 | 95.5 | −3.3 |
| 17 | Glibenclamide | 99.0 | 114.0 | 15.0 | 95.1 | −3.9 |
| 18 | Haloperidol | 92.0 | 91.3 | −0.7 | 95.7 | 3.7 |
| 19 | Lidocaine | 70.0 | 60.6 | −9.4 | 75.1 | 5.1 |
| 20 | Methadone | 89.0 | 94.3 | 5.3 | 94.0 | 5.0 |
| 21a | Methotrexate | 34.0 | 47.3 | 13.3 | 53.4 | 19.4 |
| 22 | Metoclopramide | 40.0 | 37.4 | −2.6 | 44.3 | 4.3 |
| 23 | Metronidazole | 10.0 | 16.1 | 6.1 | 15.0 | 5.0 |
| 24 | Nifedipine | 96.0 | 91.0 | −5.0 | 96.6 | 0.6 |
| 25 | Phenobarbital | 51.0 | 60.4 | 9.4 | 46.2 | −4.8 |
| 26a | Pindoioi | 51.0 | 53.6 | 2.6 | 69.0 | 18.0 |
| 27 | Prednisone | 75.0 | 58.0 | −17.0 | 69.9 | −5.1 |
| 28 | Quinidine | 87.0 | 93.8 | 6.8 | 100.0 | 13.0 |
| 29 | Ranitidine | 15.0 | 15.7 | 0.7 | 15.6 | 0.6 |
| 30 | Sulfadiazine | 54.0 | 65.6 | 11.6 | 59.1 | 5.1 |
| 31a | Sulfamethoxazole | 62.0 | 56.4 | −5.6 | 48.1 | −13.9 |
| 32 | Terbutaline | 20.0 | 39.2 | 19.2 | 25.1 | 5.1 |
| 33 | Timolol | 60.0 | 44.6 | −15.4 | 65.1 | 5.1 |
| 34 | Triamterene | 61.0 | 58.9 | −2.1 | 66.1 | 5.1 |
| 35 | Amikacin | 4.0 | −12.4 | −16.4 | 5.4 | 1.4 |
| 36a | Carbamazepine | 74.0 | 72.2 | −1.8 | 81.8 | 7.8 |
| 37 | Carbenicillin | 50.0 | 63.9 | 13.9 | 55.0 | 5.0 |
| 38 | Cefamandole | 74.0 | 78.7 | 4.7 | 76.1 | 2.1 |
| 39 | Cefazolin | 89.0 | 72.4 | −16.6 | 83.9 | −5.1 |
| 40 | Cefotaxime | 36.0 | 37.1 | 1.1 | 33.6 | −2.4 |
| 41a | Cefuroxime | 33.0 | 52.6 | 19.6 | 53.4 | 20.4 |
| 42 | Chloramphenicol | 53.0 | 37.7 | −15.3 | 47.9 | −5.1 |
| 43 | Chlorothiazide | 94.6 | 83.2 | −11.4 | 89.5 | −5.1 |
| 44 | Clonazepam | 86.0 | 83.1 | −2.9 | 80.9 | −5.1 |
| 45 | Cocaine | 91.0 | 82.2 | −8.8 | 85.9 | −5.1 |
| 46a | Dapsone | 73.0 | 69.0 | −4.0 | 66.6 | −6.4 |
| 47 | Dexamethasone | 68.0 | 78.9 | 10.9 | 73.1 | 5.1 |
| 48 | Diazepam | 98.7 | 88.7 | −10.0 | 93.6 | −5.1 |
| 49 | Ethinylestradiol | 98.0 | 86.2 | −11.8 | 92.9 | −5.1 |
| 50 | Famotidine | 17.0 | 16.2 | −0.8 | 11.9 | −5.1 |
| 51a | Fentanyl | 84.0 | 85.8 | 1.8 | 90.2 | 6.2 |
| 52 | Flecainide | 61.0 | 80.6 | 19.6 | 66.0 | 5.0 |
| 53 | Hydrochlorothiazide | 58.0 | 57.6 | −0.4 | 63.0 | 5.0 |
| 54 | Imipramine | 90.1 | 93.6 | 3.5 | 85.0 | −5.1 |
| 55 | Isoniazid | 0.0 | 17.4 | 17.4 | 5.1 | 5.1 |
| 56a | Isosorbide-5-mononitrate | 0.0 | 10.7 | 10.7 | −11.8 | −11.8 |
| 57 | Ketoconazole | 99.0 | 90.4 | −8.6 | 104.1 | 5.1 |
| 58 | Lovastatin | 95.0 | 101.3 | 6.3 | 100.0 | 5.0 |
| 59 | Mexiletine | 63.0 | 66.3 | 3.3 | 68.1 | 5.1 |
| 60 | Nitrazepam | 87.0 | 97.1 | 10.1 | 94.6 | 7.6 |
| 61a | Norethisterone | 80.0 | 76.1 | −3.9 | 88.3 | 8.3 |
| 62 | Omeprazole | 95.0 | 89.9 | −5.1 | 92.6 | −2.4 |
| 63 | Pethidine | 58.0 | 72.0 | 14.0 | 76.3 | 18.3 |
| 64 | Phenylbutazone | 96.1 | 104.5 | 8.4 | 101.2 | 5.1 |
| 65 | Propafenone | 97.0 | 79.6 | −17.4 | 91.0 | −6.0 |
| 66a | Propranolol | 87.0 | 83.4 | −3.6 | 90.3 | 3.3 |
| 67 | Pyrimethamine | 87.0 | 69.2 | −17.8 | 79.8 | −7.2 |
| 68 | Thiopental | 85.0 | 76.8 | −8.2 | 79.9 | −5.1 |
| 69 | Ticarcillin | 65.0 | 50.7 | −14.3 | 59.9 | −5.1 |
| 70 | Warfarin | 99.0 | 88.0 | −11.0 | 94.0 | −5.0 |
atest set.