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. 2014 Feb 12;78(2):320–328. doi: 10.1111/bcp.12335

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Concentration–response relationship of aspirin on arachidonic acid-mediated platelet aggregation in vitro. (A) Arachidonic acid (AA)-induced platelet aggregation at a concentration of 1.6 mmol l⁻¹ was measured in the presence of either vehicle (ethanol) or increasing aspirin concentrations. *** P < 0.001 as compared with vehicle. (B) Percentage inhibition of AA (1.6 mmol l⁻¹)-induced aggregation in the presence of different concentrations of aspirin, in aspirin-resistant vs. aspirin-sensitive subjects. , sensitivity (n = 29); , resistant (n = 2)

Inline graphic — Concentration–response relationship of aspirin on arachidonic acid-mediated platelet aggregation in vitro. (A) Arachidonic acid (AA)-induced platelet aggregation at a concentration of 1.6 mmol l⁻¹ was measured in the presence of either vehicle (ethanol) or increasing aspirin concentrations. *** P < 0.001 as compared with vehicle. (B) Percentage inhibition of AA (1.6 mmol l⁻¹)-induced aggregation in the presence of different concentrations of aspirin, in aspirin-resistant vs. aspirin-sensitive subjects. , sensitivity (n = 29); , resistant (n = 2)