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. 2014 Feb 17;78(2):353–363. doi: 10.1111/bcp.12349

Figure 4.

Figure 4

Effects of administration of warfarin [international normalized ratio (INR) 2.0–3.0] followed by rivaroxaban 20 mg once daily (od; treatment A), warfarin (INR 2.0–3.0) followed by placebo od (treatment B) and rivaroxaban alone 20 mg od (treatment C) on endogenous thrombin potential (ETP), as follows: area under the effect–time curve (AUC; A), peak (B), time to peak (C) and lag time (D). Results are relative change expressed as median ratio to baseline (n = 24–28). Inline graphic, warfarin/rivaroxaban; Inline graphic, warfarin/placebo; Inline graphic, rivaroxaban alone