Table 3.
Age-dependent changes of peripheral B cell subsets
| Phenotype | n | P-value | β (95% CI) |
|---|---|---|---|
| Total CD19+ B cells | 91 | 1·63 × 10−4 | −0·21 (−0·31, −0·10) |
| Naive B cells (CD27−) | 91 | 1·40 × 10−4 | −0·50 (−0·74, −0·25) |
| Memory B cells (CD27+) | 91 | 1·07 × 10−4 | 0·49 (0·25, 0·73) |
| Transitional (CD27−CD24hiCD38hi) | 91 | 9·09 × 10−9 | −0·20 (−0·27, −0·14) |
| Marginal zone B cells (CD27+IgD+IgM+) | 91 | 1·01 × 10−3 | 0·25 (0·10, 0·39) |
| CD5+ B cells | 70 | 2·21 × 10−4 | −0·48 (−0·73, −0·24) |
Effect of age was calculated using a linear regression model. β = beta coefficient and 95% confidence interval (CI) of the linear regression model.