Figure 3.

Coeliac disease (CD) patients on gluten-free diet (GFD) with or without mucosal deposits coded as mucosal dep⁺ and mucosal dep^–, respectively. Mucosal dep⁺ patients secreted anti-transglutaminase 2 (TG2) immunoglobulin (Ig)A antibodies into culture medium with titres significantly higher than mucosal dep^– patients. The dotted line represents the cut-off of 2·8 U/ml. The circle shows the type 1 diabetes patient on GFD for 12 years who produced low amounts of anti-TG2 antibodies; Mann–Whitney U-test.