Histograms of FDG PET volume-activity under (a): (FB) and (b): (RS) scanning conditions for patient #5. The VOI contains tumor and surrounding background (BKG), which fits with Gaussian distribution. Four threshold dotted-lines were drawn: BSL cutoff (mean + 2σ, blue), SUV (BKG + 1.8, green), 1% of the Gaussian distribution (pink), and 50% of SUVmax of the lesion (red). SUVmax for FB is lower than that for RS, due to motion smearing effect.