TABLE II.
Lesion volume assessment using threshold segmentation method in PET images. The lesion volume, mean SUV for lesion and background are listed between RS and FB. Significant differences in segmented lesion volume (p = 0.01) and the mean SUV (p = 0.01) are between RS and FB PET images, while the averaged background is similar (p = 0.15).
| Distant mean | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lesion volume | Mean SUV | TLG | liver bkgd | ||||||||||
| (cm3) | (g/ml) | (g/ml cm3) | (g/ml) | ||||||||||
| Patient | Threshold(%) | RS | FB | %Diff | RS | FB | %Diff | RS | FB | %Diff | RS | FB | %Diff |
| 1 | 50 | 1.3 | 2.0 | 54.3 | 7.5 | 6.1 | −18.9 | 9.5 | 11.9 | 24.5 | 2.4 | 2.4 | −2.1 |
| 2 | 50 | 3.4 | 6.2 | 80.1 | 6.9 | 5.2 | −23.0 | 23.3 | 32.2 | 38.5 | 2.0 | 2.2 | 7.4 |
| 3 | 50 | 12.0 | 14.2 | 17.9 | 13.9 | 10.4 | −24.6 | 166.6 | 148.0 | −11.2 | 2.6 | 3.3 | 25.0 |
| 4 | 70 | 2.2 | 6.5 | 200.0 | 5.7 | 4.4 | −22.8 | 12.2 | 28.2 | 131.5 | 2.7 | 2.7 | 0.0 |
| 5 | 50 | 2.7 | 3.6 | 32.1 | 5.0 | 4.4 | −12.1 | 13.5 | 15.7 | 16.2 | 3.1 | 2.8 | −7.8 |
| 6 | 50 | 25.7 | 51.7 | 101.1 | 10.4 | 6.6 | −36.7 | 267.0 | 339.9 | 27.3 | 3.0 | 2.9 | −1.3 |
| 7 | 50 | 3.2 | 5.8 | 78.6 | 4.8 | 3.7 | −21.9 | 15.5 | 21.6 | 39.6 | 2.4 | 2.4 | 0.0 |
| 8 | 50 | 5.6 | 5.0 | −10.4 | 11.4 | 9.7 | −14.9 | 63.5 | 48.4 | −23.8 | 2.8 | 2.8 | 1.4 |
| 9 | 50 | 1.5 | 2.5 | 72.8 | 6.5 | 4.3 | −34.7 | 9.6 | 10.8 | 13.2 | 2.8 | 2.8 | 1.4 |
| 10 | 50 | 6.9 | 7.7 | 12.8 | 6.5 | 6.0 | −8.3 | 44.5 | 46.0 | 3.4 | 2.5 | 2.5 | −0.4 |
| 11 | 50 | 11.1 | 11.7 | 6.2 | 7.6 | 6.3 | −17.9 | 84.1 | 73.4 | −12.7 | 2.2 | 2.4 | 5.8 |
| 12 | 20 | 27.6 | 35.8 | 29.8 | 10.7 | 9.2 | −14.2 | 295.5 | 329.4 | 11.5 | 3.1 | 3.2 | 2.3 |
| 13 | 60 | 6.0 | 7.1 | 19.6 | 4.0 | 4.0 | 0.3 | 23.8 | 28.6 | 19.9 | 2.7 | 2.8 | 2.9 |
| 14 | 50 | 21.3 | 30.8 | 44.5 | 8.9 | 7.3 | −18.3 | 190.3 | 224.8 | 18.1 | 3.3 | 3.1 | −6.3 |
| 15 | 50 | 2.8 | 3.5 | 23.9 | 10.4 | 9.4 | −9.3 | 29.4 | 33.1 | 12.7 | 3.1 | 3.0 | −1.6 |
| 16 | 50 | 6.2 | 5.8 | −6.3 | 6.4 | 5.3 | −17.1 | 39.3 | 30.5 | −22.4 | 3.5 | 2.9 | −17.1 |
| 17 | 50 | 2.4 | 3.8 | 56.1 | 4.6 | 4.0 | −13.1 | 11.3 | 15.4 | 35.7 | 2.0 | 2.1 | 3.9 |
| 18 | 50 | 2.2 | 8.3 | 286.5 | 3.1 | 2.9 | −8.0 | 6.7 | 23.9 | 254.6 | 1.4 | 2.0 | 40.8 |
| 19 | 50 | 10.7 | 13.2 | 23.8 | 14.1 | 18. | 28.2 | 150.4 | 238.7 | 58.8 | 2.2 | 4.3 | 94.5 |
| 20 | 50 | 13.4 | 14.7 | 9.5 | 7.3 | 8.5 | 16.3 | 98.1 | 124.8 | 27.2 | 2.6 | 3.6 | 41.4 |
| Mean | 50.0 | 47.3 | −18.4 | 17.9 | 0.6 | ||||||||
| St.dev | 9.7 | 52.1 | 9.3 | 36.0 | 8.7 | ||||||||
| p-value | 0.01 | 0.01 | 0.04 | 0.15 (>0.05) | |||||||||
| z-score | 3.8 | 2.8 | 2.2 | 1.4 (<2.0) | |||||||||