Table II.
Weight loss ≥ 5% (n = 163) |
Stable weight (n = 637) |
Weight gain ≥ 5% (n = 106) |
p-value | |
Female, n (%) | 90 (55) | 320 (50) | 66 (62) | 0.054 |
Age, years, mean (SD) | 59 (7) | 59 (7) | 58 (6) | 0.29 |
Waist, cm, mean (SD): Female Male |
99 (10) 105 (10) |
97 (11) 104 (10) |
98 (12) 104 (10) |
0.31 0.62 |
Married or cohabiting | 120 (76) | 500 (81) | 72 (69) | 0.012 |
Education years, mean (SD) | 10.7 (2.3) | 10.8 (2.3) | 10.7 (2.5) | 0.72 |
Employment, n (%): | 0.48 | |||
Employed | 78 (48) | 317 (50) | 52 (49) | |
Retired | 79 (48) | 279 (44) | 45 (42) | |
Unemployed | 6 (4) | 41 (6) | 9 (8) | |
Body mass index, kg/m2, mean (SD) | 31.1 (4.5) | 30.5 (4.3) | 30.6 (4.6) | 0.37 |
Blood pressure, mmHg, mean (SD): Systolic Diastolic |
144 (18) 86 (10) |
143 (18) 86 (10) |
137 (16) 84 (9) |
0.0012 0.042 |
Total cholesterol, mmol/l, mean (SD) | 5.46 (0.97) | 5.45 (1.00) | 5.30 (0.99) | 0.31 |
LDL cholesterol, mmol/l, mean (SD) | 3.32 (0.80) | 3.32 (0.90) | 3.17 (0.89) | 0.23 |
HDL cholesterol, mmol/l, mean(SD) | 1.48 (0.44) | 1.47 (0.38) | 1.49 (0.37) | 0.87 |
Triglycerides, mmol/l, mean (SD) | 1.52 (0.72) | 1.50 (0.69) | 1.45 (0.75) | 0.76 |
Glucose homeostasis, n (%): | 0.011 | |||
Normal | 58 (36) | 255 (40) | 51 (48) | |
IFG | 58 (36) | 234 (37) | 36 (34) | |
IGT | 32 (20) | 128 (20) | 13 (12) | |
T2D | 15 (9) | 20 (3) | 6 (6) | |
Current smoker, n (%) | 25 (15) | 85 (14) | 23 (22) | 0.094 |
AUDIT, mean (SD) | 3.80 (4.33) | 5.01 (4.98) | 5.27 (5.81) | 0.015 |
LTPA, n (%): | 0.99 | |||
Low | 64 (41) | 246 (40) | 43 (41) | |
Moderate | 47 (30) | 187 (31) | 29 (28) | |
High | 46 (29) | 180 (29) | 32 (31) | |
BDI score, mean (SD) | 5.3 (5.1) | 5.6 (5.1) | 7.6 (5.8) | 0.0025 |
BDI score ≥ 10 | 24 (15) | 101 (16) | 34 (33) | < 0.001 |
Current medication: | ||||
Beta-blockers | 30 (18) | 153 (24) | 24 (22) | 0.31 |
Diuretics | 15 (19) | 72 (11) | 11 (10) | 0.73 |
Statins | 17 (10) | 95 (15) | 17 (16) | 0.29 |
Antidepressants | 7 (4) | 22 (3) | 17 (16) | < 0.001 |
NSAIDs in regular use | 5 (3) | 13 (2) | 4 (4) | 0.47 |
Number of drugs used, median, (IQR) | 1 (0–2) | 1 (0–2) | 2 (1–3) | 0.0024 |
Notes: LDL = low-density lipoprotein; HDL = high-density lipoprotein; Mets = metabolic syndrome; IFG = impaired fasting glucose; IGT = impaired glucose tolerance; T2D = type 2 diabetes; AUDIT = Alcohol Use Disorders Identification Test; LTPA = leisure-time physical activity; BDI = Beck's Depression Inventory; NSAIDs = non-steroidal anti-inflammatory drugs; IQR = inter-quartile range.