Table 3.
388A>G and 521T>C allele and genotype frequencies in six ethnic groups of Pakistani population
| Ethnicity Genetic | Punjabi (n=30) | Sindhi (n=30) | Balouchi (n=30) | Pathan (n=30) | Kashmir (n=30) | Haz/Balt (n=30) | |
|---|---|---|---|---|---|---|---|
| Total population size (N) 180 | |||||||
| 388 | G Allele | 9.7 % | 15.1 % | 19.4 % | 16.1 % | 18.3 % | 21.5 % |
| 388 A>G Genotype | AA (Control) | 24.1 % | 18.4 % | 13.8 % | 17.2 % | 14.9 % | 11.5 % |
| AG (Heterozygous) | 11.1 % | 16.7 % | 20.4 % | 16.7 % | 16.7 % | 18.5 % | |
| GG (Homozygous) | 7.7 % | 12.8 % | 17.9 % | 15.4 % | 20.5 % | 25.6 % | |
| 521 | C Allele | 11.1 % | 8.9 % | 15.6 % | 11.1 % | 31.1 % | 22.2 % |
| 521 T>C Genotype | TT (Control) | 18.5 % | 19.3 % | 17 % | 18.5 % | 11.9 % | 14.8 % |
| TC (Heterozygous) | 15 % | 5 % | 20 % | 15 % | 30 % | 15 % | |
| CC (Homozygous) | 8 % | 12 % | 12 % | 8 % | 32 % | 28 % | |