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. 2014 Jul 29;143(1):120–129. doi: 10.1111/imm.12294

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© 2014 The Authors. Immunology published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Effect of sialoadhesin-deficiency on passive immune complex trapping upon follicular dendritic cells (FDC) and lectin-mediated endocytic uptake in the marginal zone (MZ). (a, b) Effect of sialoadhesin-deficiency on the ability of FDC to trap pre-formed peroxidase–anti-peroxidase (PAP) immune complexes. Sections were immunostained to detect FDC (CD35⁺ cells, red) and PAP (rabbit IgG, green). (c, d) The trapping of dextran-FITC within the splenic MZ is unaltered in sialoadhesin-deficient (Sn^−/−) mice.