Table IV.
Adjusted odds ratio (OR) and 95% confidence interval (CI) of metabolic syndrome risk according to varying concentrations of liver markers.
| Liver markers | Men
|
Liver markers | Women
|
||
|---|---|---|---|---|---|
| ORa | 95%CI | ORa | 95%CI | ||
| AST (units/L) | AST (units/L) | ||||
| ≤22 | 1.00 | Reference | ≤18 | 1.00 | Reference |
| 23–25 | 1.45 | (0.59–3.58) | 19–21 | 1.06 | (0.52–2.15) |
| 26–31 | 1.63 | (0.68–3.91) | 22–25 | 0.90 | (0.44–1.84) |
| >31 | 1.83 | (0.75–4.45) | >25 | 1.53 | (0.80–2.92) |
| p for trend = 0.188 | p for trend = 0.284 | ||||
| ALT (units/L) | ALT (units/L) | ||||
| ≤21 | 1.00 | Reference | ≤13 | 1.00 | Reference |
| 22–28 | 0.91 | (0.33–2.55) | 14–17 | 0.66 | (0.27–1.63) |
| 29–40 | 1.69 | (0.70–4.06) | 18–23 | 1.85 | (0.82–4.15) |
| >40 | 2.77 | (1.18–6.53) | >23 | 2.55 | (1.22–5.35) |
| p for trend = 0.007 | p for trend < 0.001 | ||||
| AST: ALT ratio | AST: ALT ratio | ||||
| ≤0.71 | 1.00 | Reference | ≤0.98 | 1.00 | Reference |
| 0.72–0.89 | 0.54 | (0.26–1.14) | 0.99–1.21 | 0.35 | (0.19–0.64) |
| 0.90–1.14 | 0.32 | (0.14–0.74) | 1.22–1.47 | 0.24 | (0.11–0.53) |
| >1.14 | 0.31 | (0.12–0.79) | >1.47 | 0.19 | (0.07–0.49) |
| p for trend = 0.004 | p for trend < 0.001 | ||||
| ALP (units/L) | ALP (units/L) | ||||
| ≤58 | 1.00 | Reference | ≤50 | 1.00 | Reference |
| 59–67 | 3.06 | (1.20–7.82) | 51–61 | 0.90 | (0.37–2.18) |
| 68–80 | 3.07 | (1.18–8.00) | 62–73 | 1.12 | (0.48–2.59) |
| >80 | 3.72 | (1.49–9.29) | >73 | 1.53 | (0.67–3.49) |
| p for trend = 0.011 | p for trend = 0.162 | ||||
a
Adjusted for age, education, smoking status, alcohol intake, body mass index and level of physical activity Separate models were estimated for men and women.